Duration of anticoagulatoin
Cancer
≥ 2 idiopathic deep vein thromboses
distal deep vein thrombosis (below knee)
Important causing risk factors :
Surgical intervention
Severe comorbidity
Immobilized leg (cast, splint, stroke)
Less important causing risk factors :
Estrogens (oral contraceptiva, estrogen substitution)
Low risk thrombophilia :
Heterozygous forms of :
Factor-V Leiden
Mutation of prothrombin gene
High risk thrombophilia :
Presence of :
Deficiency of protein C or protein S
Anti-phospholipid antibodies
Homozygous forms of :
Factor-V Leiden
Mutation of prothrombin gene
Heterozygous forms of :
Factor-V Leiden + Mutation of prothrombin gene
Recommended duration of oral anticoagulation :
Label